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Serum metabolomics reveals irreversible Inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity

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L- Carnitine 200mg/ml (100ml Bottle)

Ketone Bodies Are Mildly Elevated in Subjects with Type 2 Diabetes Mellitus and Are Inversely Associated with Insulin Resistance as Measured by the Lipoprotein Insulin Resistance Index

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For non-targeted metabolomic analysis, samples were prepared by protein precipitation using acetonitrile and ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight electrospray ionization (ESI) mass spectrometry (UPLC-QTOF-ESI-MS) was conducted in both positive and negative ionization modes