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Additionally, the combined treatment led to an increased abundance of malondialdehyde (MDA), an indicator of lipid peroxidation, and the morphological characteristics of ferroptosis in H1299 cells, including rounded and shrunken mitochondria and the disappearance of mitochondrial inner ridges (Fig

8

Some other experimental studies have given another explanation for the improved carbohydrate metabolism, that LCA supplementation can reduce the ratio of acetyl-CoA to free CoA in the mitochondria, thereby stimulating the activity of pyruvate dehydrogenase (PDH) ( via LCA in AF suppression

Sarchielli 2006)

Several hypotheses were made about the health effects of fermented foods such as nutritive alteration of food ingredients and the biosynthesis of different compounds, variations of the gut microbiota, and the immune system modulation [152]