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10.1021/acs.nanolett.0c04713 19 BoremR.MadelineA.BowmanM.GillS.TokishJ.MercuriJ

mAbs-based approaches In MM, radiolabeled daratumumab, known for its high affinity and specificity for CD38, has been used as a diagnostic tracer for imaging purposes in both preclinical [101, 102] and clinical studies [65, 103]

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The introduction of wortmannin was found to significantly reverse the expression of PI3K and AKT, as well as the anti-apoptotic and anti-inflammatory effects of Dihexa, resulting in a decrease in the number of neuronal cells present in the cortex and the levels of IL-10, and an increase in the levels of TNF-alpha and IL-1-beta [1]

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