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Description
In this context, ferroptosis exerts a context-dependent double-edged sword effect [127]: while targeted induction of ferroptosis in hyperproliferative PASMCs could theoretically reverse remodeling, uncontrolled ferroptosis leads to deleterious vascular injury [128, 129]
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The Research Ethics Committee from the Federal University of So Paulo and financed by The So Paulo Research FoundationFAPESP no 2015/13308-9
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Clinical trials including the STEP program demonstrated that participants using semaglutide lost between 10% and 22% of body weight over 68 weeks, depending on dosage and adherence
