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Studies selected to review were based on the following exclusion and inclusion criteria

doi: 10.1007/s43032-021-00506-5

Price et al., 2013)

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells

This versatility in administration route is practically important because neuropathy often affects diffuse nerve territories rather than a single discrete injury point

The GSH depletion was the earliest event in BSO plus HCH-induced signaling and the apoptotic effect of this combination was correlated with the enhanced depletion of GSH as glutathione precursor GME abrogated activation of JNK, ERK and the apoptosis