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Ferroptosis is characterized by ROS generation, GPX4 depletion, LOOH accumulation, and iron overload [14]

Roginsky et al

4 , 57 , 99 Further studies have identified distinct melanocyte subpopulations in the human scalp using c-KIT/CD117 microbeads, revealing variations in melanosome markers and the presence of immature melanocytes

suggests that TB-500 may interact with cell movement as it binds globular actin (G-actin) and may modulate how actin filaments assemble to plausibly make endothelial cells more able to change shape, migrate, and form multicellular structures