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It is notable that previous studies have suggested that the chrM:302 site serves as a rheostat for mtDNA replication versus transcription, which are functionally linked in mitochondria 3,45
A lack of sleep is linked to increased levels of oxidative stress, hormone imbalances, and even decreased levels of glutathione
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doi: 10.2741/4459
409 Moreover, resistant CCRF-CEM cells with high QPRT activity exploit amino acid catabolism as a substitute pathway for NAD + generation
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