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Contraindications remain somewhat speculative given limited human data

& Linderman, J

Niu X, Pei WY, Ma JF

Sperm-specific piRNA expression decreases by 45%, leading to retrotransposon activation and increased genomic instability ( 5.2 Generational impact analysis The reproductive consequences of EED exposure demonstrate remarkable persistence, extending beyond the directly exposed (F0) generation to affect subsequent offspring (F1-F3) through distinct but interconnected mechanisms

In one study, kisspeptin-10 increased the average serum testosterone levels within 24 hours of injection

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