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1,6 Surgery is required when the symptoms of CD cannot be controlled using medication alone, and for complications such as bowel obstructions, abscess, fistulas, or perforated bowel

Zeng Z, Huo X, Zhang Y, Xiao Z, Zhang Y, Xu X

[22] Symptoms of B12 Deficiency Signs of B12 deficiencies include [23] [24] [25] [26] [27] Chronic fatigue Psychiatric problems Neurological problems Increased risks of Alzheimers disease Intergenerational neurological disorders B12 Dosage

Refer to Table 3: Treatment of B 12 deficiency for supplementation routes, dosage and duration

Research suggests a direct link between B12 levels and mental health