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Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments

90 Histone demethylase KDM3B is another potential epigenetic regulator of ferroptosis, as it upregulates the expression of SLC7A11, indicating that ferroptosis is influenced by epigenetic mechanisms

This study shows that glucocorticoids dynamically regulate mitochondrial function, pointing at a direct mechanism through which stress hormones can remodel brain energetics and behaviour

Nuclear factor E2-related factor 2 (Nrf2) can reduce the expression of TfR1, regulate iron metabolism, maintain the balance of intracellular iron homeostasis, and limit the production of reactive oxygen species (ROS), thereby reducing ferroptosis (Li S