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doi: 10.1016/j.peptides.2014.08.005

Wong, J

Hydration needs should be individualized, particularly for those with heart failure, kidney disease, or other conditions requiring fluid management

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This can mean that the material is not easily eliminated from the body The cause of constipation is often not known

Based on the above, we strongly believe that only prospective studies designed according to a precise stratification of the above-mentioned risk factors and considering their temporal impact on PsA development [8] may clarify whether biologics prevent the transition toward a clinical PsA