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Description
Immediately after the sacrifice, the stomach was removed and the lesions were assessed by unbiased observers

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suffering from nervous system diseases (e.g., epilepsy, schizophrenia, etc.)
Some people who used Accutane reported undesirable side effects like worsening acne or other undesirable side effects

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Consistently, mechanistic studies indicate that the longevity-promoting transcription factor SKN-1/nuclear factor erythroid 2-related factor (Nrf) is required for biguanide-mediated lifespan extension (Cabreiro et al., 2013
