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Neuroscientist 22 , 447463 (2016)

Vitamin B12 deficiency in the mother during pregnancy and whilst breastfeeding, or in the child after birth, can lead to the severe degeneration of the childs nervous system and brain (47)

Journal of AOAC International

In addition, nitrous oxide administration during labor may be a contributing risk factor for infants prone to developing vitamin B12 deficiency (154)

Yes, both are generally safe under medical supervision

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