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Since both CIPN and hearing loss are dose-related, they occur concurrently in many patients but there is not a clear mechanistic or risk-based relationship between these effects

Hashimotos thyroiditis: Hashimotos thyroiditis is an autoimmune disease in which the immune system attacks the thyroid gland, leading to hypothyroidism

Most of the -adrenergic antagonists are exclusively metabolized or biotransformed in the liver and then renally eliminated

Chemistry-Anti-Cancer Agents 23 (2), 210221

Not only is it formulated to tackle current breakouts, it's also meant to help prevent future breakouts
