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23.Kaminetsky J, Werner M, Fontenot G, Wiehle RD

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DAMPs such as HMGB1, IL-33, and ATP released from liver injury bind to TLR2/4 and activate hepatic stellate cells (HSC), prompting their transformation into myofibroblasts and secretion of a large number of extracellular matrix proteins, which leads to matrix deposition and fibrosis [277, 316, 317]

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M., Czyzyk, A., Meczekalski, B., & Genazzani, A

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Peroxyl radicals (RO) RO are an important class of ROS primarily generated within cells through lipid peroxidation chain reactions, particularly in the regions rich in unsaturated fatty acids located in cell membranes [62]

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