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AACR 2013, 2012

501 Nicotinamide, as a competitive inhibitor of sirtuins, specifically reduces the phosphorylation of tau (Thr231), which is related to microtubule depolymerization in an analogous manner to that of SIRT1

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At the phylum level, TM7 was significantly positively correlated with acetate content ( p 0.05), indicating that heat stress had an adverse effect on rumen fermentation process of dairy cows and reduced the production of all VFAs