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One of the most obvious signs of aging starts with our skin

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See this article for more information about his-tags and other peptide affinity tags such as FLAG tags and strep tags, and this article for more information about GST and other solubility tags such as MBP and SUMO

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With aging, the gradual accumulation of atherosclerotic risk factors, including oxidative stress, inflammation, dyslipidemia, and hyperglycemia, drives metabolic reprogramming in ECs, particularly in regions exposed to disturbed flow with OS, ultimately leading to EC dysfunction and atherosclerosis
