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318 (Pt A), 116932

The discovery that the synthetic compound MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a substrate of MAOB, which converts this compound to the neurotoxin MPP + (1-methyl-4-phenylpyridinium), causing a parkinsonism syndrome in some mouse strains and primates including humans, provided a basis for our understanding of the participation of MAO in dopaminergic neurodegeneration, and MAOB inhibitors as neuroprotective drugs with disease-modifying activity

56 , 268314 (2018) D

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Marino Y., Arangia A., Cordaro M., Siracusa R., DAmico R., Impellizzeri D., Cupi R., Peritore A.F., Gugliandolo E., Fusco R., et al

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