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Description
Pharmacokinetic modelling suggested a 3compartmental distribution with mean residence times of 1 h (central compartment), 12 h (fast equilibrating compartment such as liver and kidney) and 191 h (slow equilibrating compartment such as skeletal and cardiac muscle), suggesting that transfer of Lcarnitine from plasma to the main carnitine pool is a slow process taking days to weeks

In diseases where amino-acid metabolizing enzymes are dysfunctional or absent (e.g., propionic acidemia and methylmalonic acidemias characterized by neurological symptoms, muscle weakness and low energy) C3 accumulates, and higher blood levels are used as a screening tool

Free Report Silva AR, et al

Do not use the dietary supplement as a substitute for a complete and balanced diet

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And it may affect the metabolism of certain seizure medications
