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In these models it has been demonstrated an increased excitatory synaptic neurotransmission resulting in decreased apical and basal dendritic spine densities without compensatory changes in synaptic inhibition [116,117]

Reactive oxygen species-scavenging scaffold with rapamycin for treatment of intervertebral disk degeneration

Site-directed mutagenesis experiments show that cysteine-553 in human GLCLC is involved in heterodimer formation between the catalytically active GLCLC and the auxiliary, activity-enhancing GLCLR unit, which likely occurs through a disulfide bond [139]

Lysine crotonylation (Kcr) has been shown to be a type of histone protein PTM by Tan et al

Histone code and higher-order chromatin folding: a hypothesis

The microbiota-gut-brain axis is a bidirectional communication system linking microbial, immune, and neural signaling pathways that regulate neurodevelopment and behavior [19, 20]