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In animal models of I/R injury, curcumin has been shown to attenuate BBB breakdown and improve cognitive function, suggesting its potential as a neuroprotective agent in BBB-related disorders (Wang et al., 2019

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Specific DNA methylation at CpG and non-CpG sites is essential for chromatin regulation

The methionine precursor DL-2-hydroxy-(4-methylthio)butanoic acid protects intestinal epithelial barrier function

Neurofibromatosis syndrome type 1 is caused by a mutation in the NF1 gene, which is located in the long arm of chromosome 17 as 17q11.2
