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Preclinical studies indicated that it targeted the bacterial flavoenzyme TrxR, essential for M.tb survival by protecting against oxidative and nitrosative stress
Formation of acetaldehyde-derived DNA adducts due to alcohol exposure

Energy Balance Pathways: Studying integrated metabolic response mechanisms

Researchers propose that MOTS-c acts as an endocrine-like factor a mitochondrial hormone that helps coordinate metabolism and stress responses across the body, thereby affecting the aging process

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Normally, FOXO4 binds to p53, preventing senescent cells from undergoing apoptosis