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doi: 10.1042/0264-6021:3380569

624 The MEK-ERK kinase pathway primarily regulates methylation, and the inhibition of any protein in the ERK pathway could ultimately lead to the downregulation of DNMTs

A reduction in glycolytic progress was detected in erastin-induced ferroptosis, which might be caused by increased synthesis of ATP and oxidative phosphorylation (OXPHOS)[10, 115]

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St Jude Childrens Research hospital have demonstrated an increase in the 3-year OS and EFS in non chemo-refractory recipients receiving CD45RA-depleted grafts (78.9% and 77.7%, respectively) compared with historic T-cell depleted haploHSCT cohorts (46.7% and 42.7%, respectively, p = 0.004, and 0.003)

Traditional combination of chemotherapy with photodynamic therapy often suffers from high systemic toxicity, poor spatiotemporal coordination, and increased cumulative side effects
