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The needle breaks up the contracted sarcomeres (the smallest contractile units of muscle fiber), interrupts the abnormal acetylcholine feedback loop, and creates a local microtrauma that stimulates a healing response

Ive just forwarded this onto a coworker who was conducting a little homework on this

In research contexts, investigators typically define model-specific controls, endpoints (for example, scratch-wound assay closure metrics, transwell migration, TEER and barrier-integrity markers, cytokine panels, ECM-related markers), and time points

& Peters, J

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Peptide Regulations Are Changing