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Stiff-person syndrome: insights into a complex autoimmune disorder
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Mutations in GBA1 represent one of the most common genetic risk factors for PD, leading to significantly reduced GCase protein activity in cholinergic neurons and impairing -syn metabolism, thereby elevating -synuclein levels in these neurons [179]
10.1371/journal.pone.0049215
As a thioredoxin, SELENOT likely plays a neuroprotective role in redox homeostasis in neurons during brain ontogenesis
