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Blackstock CD, Higashi Y, Sukhanov S, Shai SY, Stefanovic B, Tabony AM, et al

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Depending on the signals received in the plaque microenvironment, recruited monocytes can assume variety of macrophage identities including inflammatory macrophages, aortic intima-resident macrophages (Mac AIR ), and type I interferon-inducible cells

Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species

If these are unclear, it is safer to avoid treatment