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A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta-4 in healthy volunteers

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After one-third of the study participants have been enrolled and completed follow-up, the DSMBs will review the data and make recommendations concerning continuation, modification or termination of the study due to unexpectedly large beneficial effects or serious side effects and can suggest extension of the trial should the primary outcomes occur less often than anticipated

This can stimulate angiogenesis at sites of tissue disruption in animal models ERK1/2 activation: Studies in preclinical settings have observed activation of extracellular signal-regulated kinases

Overall, AOD-9604 appears safe, with a profile similar to a placebo