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[DOI] [PMC free article] [PubMed] [Google Scholar] Carmona-Rosas G, Hernndez-Espinosa DA, Alcntara-Hernndez R, Alfonzo-Mndez MA, Garca-Sainz JA

MOTS-c is a mitochondrial-derived peptide that plays a key role in regulating metabolic function, enhancing fat metabolism, and improving energy levels by optimizing mitochondrial efficiency

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JAMA 282 , 15681575 (1999)

In practice, studies seem to show that both options give similar results