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Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells

VGF is a member of the granin family, and the coordination among its family members plays a crucial role in the biogenesis of secretory granules 22

BPC-157, a synthetic peptide, shows promise in strengthening the immune system

This mechanism suggests BPC-157 functions as a cellular sensitizer to endogenous growth factors rather than as a direct growth factor itself

MusthafaQAAbdul ShukorMFIsmailNASMohd GhaziAMohd AliRNorIFet alOxidative status and reduced glutathione levels in premature coronary artery disease and coronary artery disease

As with any emerging therapy, we prioritize individualized assessment, careful monitoring, and evidence-informed recommendations for every patient