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Description
The necrotic area in the distal portion of the skin flap was easily demarcated by gross observation [30]

However, rare serious complications may occur in some patients receiving VPA chronically, including fatal haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (VHE)

B.PettingerM.RossouwJ.MartinL

doi: 10.2337/dc14-2852 58

doi: 10.1002/jmd2.12292

Journal of the American College of Cardiology, 64 , 19081914
