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At the central level, excessive prolactin inhibits the synthesis and pulsatile secretion of hypothalamic gonadotropin-releasing hormone (GnRH), thereby reducing the release of pituitary gonadotropins, luteinizing hormone and follicle-stimulating hormone, ultimately leading to hypogonadism (57)

A Common Feature of Pesticides: Oxidative StressThe Role of Oxidative Stress in Pesticide-Induced Toxicity

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As a result, it was recently reported that primordial germ cell-like cells were generated in vitro from pluripotent stem cells (PSCs) of rats, albeit a decade later than in mice 36

Flynn RS, Murthy KS, Grider JR, Kellum JM, Kuemmerle JF: Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohns disease