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Zinc dysregulation within the endolysosomal system also intersects with cancer biology: the alcohol-deterrent and emerging anticancer agent disulfiram disrupts endolysosomal structure and raises intraluminal zinc in breast cancer cells, implicating zinc dysregulation in its cytotoxicity and suggesting that extracellular zinc availability modulates its efficacy 169
Gene Ontology (GO) enrichment analysis indicated that DEGs were significantly enriched in biological processes such as mitochondrial protein processing and regulation of protein processing involved in protein targeting to mitochondrion
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Pada kondisi ini, resistensi insulin dan pembakaran lemak pun semakin meningkat
