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Because vitamin B 12 in supplements is not bound to protein, and because intrinsic factor (IF) is still available, the absorption of supplemental vitamin B 12 is not reduced as it is in pernicious anemia

These systems can model neurovascularglial interactions, BBB dysfunction and the combined astrocytemicroglia effects on oligodendrocyte survival and myelination, thereby enabling concurrent assessment of neuronal health, myelin dynamics, immune activation and vascular integrity with high experimental accessibility

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The same observation was made in regard to scavenger receptor CD36 expressed by circulating monocytes