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injections varied depending on the test animal, reaching levels of approximately 1419% and 4551% in rats and beagle dogs, respectively

CNS, central nervous system

Oliai Araghi S, Kiefte-de Jong JC, van Dijk SC, Swart KMA, van Laarhoven HW, van Schoor NM, de Groot LCPGM, Lemmens V, Stricker BH, Uitterlinden AG, van der Velde N

benzyl alcohol has been associated with serious adverse events (the gasping syndrome) in newborns and must be avoided in this population

This tetrapyrrole-derived ring is unusual in that it has undergone a ring-contraction process meaning that one of the bridging ( meso ) carbon atoms that are used to connect the four pyrrole rings has been eliminated, thereby generating a macrocycle that is both contracted and lop-sided in comparison to the tetrapyrrole-frameworks that are associated with heme and chlorophylls [10]

Evidence for platelet involvement and probucol-sensitive mechanism