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Studies such as this have led to recent clinical trials testing the safety and tolerability of intranasal delivery of GSH to patients with PD [24]

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Nature 502, 327332

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Comprehensive characterization of this system using systems biology approaches ( Figure 1 The COSM ro analysis of the SCC-61/rSCC-61 system produced data consistent with these findings, confirming the expected routing of glycolysis into the pentose phosphate pathway (PPP) needed to generate reducing equivalents in the form of NADPH and nucleotide building blocks for the repair of radiation-induced DNA damage