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After SCI, the expression levels of DMT1 and TFR in the white matter of the spinal cord are significantly increased, resulting in iron deposition

10.1016/j.cophys.2019.04.013
L.ViaJ

Since GSH is a co-factor essential for the formation of S-D-lactoylglutathion by Glo1, and is released again in the formation of D-lactate by Glo2, a decrease in Glo2 activity might explain the reduced GSH availability

Given the data suggesting hyperferritinemia in patients with severe COVID-19, ferroptosis can be a significant contributor to tissue damage in COVID-19 illness

Similar content being viewed by others Introduction Parkinsons disease (PD) is a progressive neurological disorder manifested clinically in four cardinal motor symptoms