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The high amount of released glutamate causes decreased concentration of gamma-aminobutyric acid (GABA) confirmed by MRI localized spectroscopy of brain metabolites

10.1016/j.eururo.2015.03.031 18 ChenZ.HanX.OuyangX.FangJ.HuangX.WeiH

These results indicate that cagrilintides metabolic effects are receptor-dependent and that functional AMY1R/AMY3R signaling is essential for proper nutrient partitioning and energy balance regulation

Science 371 , eaba8310 (2021)

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Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach