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Prophylactic supplementation may be considered for select high-risk patients, particularly those with strict vegan diets, post-bariatric surgery, or on long-term metformin therapy

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These findings together with the pmk-1 -dependent induction of hsp-70 suggest that in response to a toxic insult by the volatile BA, LROs and PMK-1 cooperate in the elicitation of stress and antimicrobial defenses