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Combination therapies targeting both neoplastic cells (Schwann cells) and cells of the tumour microenvironment might be more effective than drugs targeting only the tumour cells

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According to these premises, the role of an oral supplement such as Uroial PLUS , which include all the previously reported compounds, could represent a novelty in the urological panorama due to the high concentrations of D-mannose (3000 mg), chondroitin sulphate (500 mg), NAC (600 mg), and hyaluronic acid (35 mg)

We observed that the deficiency of TFE3 , but not TFEB , in GBM cells, led to a reduction in both the number and size of spheres in vitro (Fig

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103 Moreover, altered cytokine production, impaired phagocytosis, and reduced lymphocyte proliferation are among the functional changes observed