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This may be explained by an increased propensity of flavoproteins to aggregate upon riboflavin depletion, as truncated apo-NQO1 coaggregated less with A42 than did wild-type apo-NQO1

doi: 10.1210/en.2004-1565

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By integrating mechanistic discoveries with emerging therapeutic innovations, the analysis highlights how DDS research is laying critical groundwork for future translational efforts

However, efforts to link these effects specifically to dietary carotenoid levels have failed to show a correlation

EggersdorferMKraemerKCordaroJBFanzoJGibneyMKennedyEet al