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FBXW7 contributes to circadian rhythmicity by targeting mTOR, a key regulator of circadian translation, for ubiquitin-mediated degradation, resulting in opposing oscillations between FBXW7 and mTOR protein levels and enabling rhythmic control of translational output (Okazaki et al., 2014

The rapid mobilization of cholesterol from adipose stores saturates bile

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Notably, this model showed no NFTs or amyloid plaques
