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I., Ambarus C., Bajko Z., Motoc A

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While PDGFs have originally been identified as growth factor for smooth muscle cells (176), they are nowadays viewed as potent inducer of oligodendrocyte proliferation and differentiation (177, 178)

It was observed that oral consumption of curcumin alters the ratio between beneficial and harmful bacteria in the gut microbiota community and enhances the function of intestinal barriers like the one containing alkaline phosphatase involved in detoxification of bacterial lipopolysaccharide and mucosa, which inhibits the entry of pathogens into the body (Balaji et al., 2025)

Finally, astrocytes are fundamental for brain resilience and brain compensation through numerous neuroprotective systems (again glutamate clearance, K + buffering and ROS scavenging), through reactive astrogliosis, which protects the nervous tissue against acute lesions and limits chronic disorders 118 , and through supporting postlesional regeneration 119,120