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Analysis of the natural human IgG antibody repertoire: life-long stability of reactivities towards self antigens contrasts with age-dependent diversification of reactivities against bacterial antigens
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NCR-1 and NCR-2 are lysosome-associated proteins Human NPC1 contains a dileucine lysosome-targeting motif (LLNF) in the cytoplasmic tail (Figs S1 and S2) (60) and is located in a subset of the endosome/lysosome (61, 62)
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Rosen RC, Diamond LE, Earle DC, Shadiack AM, Molinoff PB
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