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Cellular electron cryotomography: toward structural biology in situ

Based on the modeled PDZD-8 structure, we hypothesized that changing leucine-98 and isoleucine-252 of the PDZD-8 SMP domain to tryptophan (W) would block lipid insertion into its hydrophobic groove (Supplementary Fig

J Obstet Gynaecol 2003;23:653-6

Dietary cholesterol is a major source of cholesterol in humans, and its uptake by enterocytes is mediated by the NPC1L1 protein [14]

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It has been hypothesized that supplementation may also boost conception rates and enhance the effectiveness of reproductive therapies