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A second hydrogen peroxide molecule acts as a reducing agent to regenerate the resting state enzyme, producing a molecule of oxygen and water.36 Hydrogen peroxide though at low amounts tends to regulate some physiological processes such as signaling in cell proliferation, cell death, carbohydrate metabolism, mitochondrial function, and platelet activation and maintenance of normal thiol redox-balance,37 however, at high concentrations it has been reported to be very deleterious to cells.38 Hence, the ability of CAT to effectively limit H2O2 concentration in cells underlines its importance in the aforementioned physiological processes as well as being a first line antioxidant defense enzyme

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In addition, decreased glucose uptake is strongly associated with reduced protein O -GlcNAcylation that directly links altered brain metabolism with AD pathological hallmarks (395, 396)

Low glycemic index diet is used for body weight regulation and glycemia control in individuals with diabetes mellitus

Different activation of immune-related genes in honey bee nurses and foragers ( Apis mellifera )