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The involvement of intestinal microbiota with the complex network of human organs is mediated by microbial metabolism in CKD, and intestinal-cardiac as well as intestinal-brain axes increase cardiovascular risk and may play a role in neuropsychiatric diseases (Cosola et al., 2019)

Also, hypothalamic-pituitary-adrenal insufficiency in patients with CFS has been described as a result of activation of the immune and inflammatory pathways [4]

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The absence of TMA in the urine of germ-free mice without microbiota, 66 the suppression of TMAO production from dietary choline 22 and carnitine 19 in mice treated with broad-spectrum antibiotics, and the re-increase in plasma TMAO levels after antibiotic withdrawal clearly indicate the role of gut microbiota in TMA and TMAO production

The effects of tyrosine on cognitive performance during extended wakefulness

External counterpulsation enhances neuroplasticity to promote stroke recovery