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The reduction usually does not stop at the mixed-disulfide species because the second thiol of DTT has a high propensity to close the ring, forming oxidized DTT and leaving behind a reduced disulfide bond

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It is primarily stored in the mitochondria the energy-producing structures within cells where it plays a vital role in converting methylmalonyl-CoA to succinyl-CoA, a key step in the citric acid cycle that supports energy production

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Download this stock image: Glutathione or GSH is an antioxidant in plants, animals, fungi, and some bacteria and archaea