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Because conditions like pernicious anemia are lifelong, prescription B12 therapy is often indefinite

Rahimian, R., Belliveau, C., Chen, R

[DOI] [PubMed] [Google Scholar] 77.Becejac T., Cesarec V., Drmic D., Hirsl D., Madzarac G., Djakovic Z., Bunjevac I., Zenko Sever A.A., Sepac A., Vuletic L.B., et al

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The model is that changing from one type to another is a consequence of overexpression of the "master" gene inhibiting another
