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Matsushita M, Freigang S, Schneider C, Conrad M, Bornkamm GW, Kopf M

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The authors identified multiple cells responsible for immunosuppressive functions in dendritic cells, exhausted T cells and Tregs, refining local tumor structures

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Insulin resistance is the hallmark of metabolic syndrome an increasingly common disorder diagnosed by the presence of three of five metabolic abnormalities: high blood pressure, elevated fasting triglycerides, low levels of beneficial HDL cholesterol, increased abdominal circumference, and high fasting blood glucose (Bassi 2014