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Some observational studies have suggested a correlation between low Se levels and an increased risk of developing goiter or thyroid nodules

Even Miyamae et al
doi: 10.3390/ijms141019846
Hu S, Lin Z, Zhao S, Zhang B, Luo L, Zeng L

For serum preparation, blood samples were incubated for 1 h at room temperature and then centrifuged (1,950 x g, 15 min, Varifuge 3.0, Heraeus, Hanau, Germany) and stored at -80C prior to further analysis

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